RPI Structural Bioinformatics Lab

The Rensselaer Polytechnic Institute Structural Bioinformatics Laboratory pursues dynamic structure – function studies of proteins. The lab combines computational methods with biophysical data to elucidate mechanisms of biological processes.


Proposed mechanism by which FDA-approved hepatitis C virus (HCV) drugs synergize with the SARS-CoV-2 antiviral remdesivir

Research Highlights

Hepatitis C virus drugs inhibit SARS-CoV-2 PLpro and act synergistically with the antiviral remdesivir

Article

Press Release

Interdomain dynamics in a complex formed between Maloney Leukemia Virus and Host Chromatin-associated proteins

Interdomain dynamics in a complex formed between Maloney Leukemia Virus and a host chromatin-associated protein

Milestones

Congratulations to Mr. Chris Damone who has accepted a position as Area Manager Intern at Amazon for summer 2021!

Congratulations to Ms. Jingzhou Hao, awarded Highest Honors for her Rutgers University undergraduate research thesis Conformational Dynamics of Murine Leukemia Virus Integrase in its Complex with Chromosomal Bromodomain-Containing Protein 3 Structure (Cell Press) 2021

Image of Harold Scheraga
1921 – 2020

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Harold A. Scheraga

Harold was gifted with a unique combination of intensity and breadth of vision. He realized early in his career that both experimental and theoretical work would be necessary to solve the central problems of protein science, and, most unusually, he excelled in both spheres.