RPI Structural Bioinformatics Lab
The Rensselaer Polytechnic Institute Structural Bioinformatics Laboratory pursues dynamic structure – function studies of proteins. The lab combines computational methods with biophysical data to elucidate mechanisms of biological processes.
Hepatitis C virus drugs inhibit SARS-CoV-2 PLpro and act synergistically with the antiviral remdesivir. Cell Reports 2021
Comparison of (left) backbone and (right) sidechain structures of NMR (green) and AlphaFold2 model (blue) of CASP target T1055.
Assessment of prediction methods for protein structures determined by NMR in CASP14: Impact of AlphaFold2. PROTEINS 2021. Article
Welcome to Ms. Kassie Hooker, Master of Science in Clinical and Translational Research Sciences, University of Cincinnati, starting as Research Project Coordinator in our lab!
Welcome to Dr. Anna DeFalco, Ph.D. in Chemistry, Pontifical Catholic University, Rio de Janeiro, Brazil and Masters Degree in Public Health, starting as Postdoctoral Associate in our lab!
Welcome to Dr. Namita Dube, Ph.D. in Computational Chemistry, University of Cambridge, starting as Research Scientist in our lab!
RPI Faculty Awarded Shared Instrument Grants for 800 MHz NMR System Upgrade and Helium Recovery System. Article.
Harold was gifted with a unique combination of intensity and breadth of vision. He realized early in his career that both experimental and theoretical work would be necessary to solve the central problems of protein science, and, most unusually, he excelled in both spheres.
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